The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum

Members of the haloacid dehalogenase (HAD) family of metabolite phosphatases play an important role in regulating multiple pathways in Plasmodium falciparum central carbon metabolism. We show that the P. falciparum HAD protein, phosphoglycolate phosphatase (PGP), regulates glycolysis and pentose pat...

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Detalles Bibliográficos
Autores principales: Dumont, Laure, Richardson, Mark B., van der Peet, Phillip, Marapana, Danushka S., Triglia, Tony, Dixon, Matthew W. A., Cowman, Alan F., Williams, Spencer J., Tilley, Leann, McConville, Malcolm J., Cobbold, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904873/
https://www.ncbi.nlm.nih.gov/pubmed/31822583
http://dx.doi.org/10.1128/mBio.02060-19

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