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Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization
The first immunization in a protein prime-boost vaccination is likely to be critical for how the immune response unfolds. Using fine needle aspirates (FNAs) of draining lymph nodes (LNs), we tracked the kinetics of the primary immune response in rhesus monkeys immunized intramuscularly (IM) or subcu...
Autores principales: | Havenar-Daughton, Colin, Carnathan, Diane G., Boopathy, Archana V., Upadhyay, Amit A., Murrell, Ben, Reiss, Samantha M., Enemuo, Chiamaka A., Gebru, Etse H., Choe, Yury, Dhadvai, Pallavi, Viviano, Federico, Kaushik, Kirti, Bhiman, Jinal N., Briney, Bryan, Burton, Dennis R., Bosinger, Steven E., Schief, William R., Irvine, Darrell J., Silvestri, Guido, Crotty, Shane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905039/ https://www.ncbi.nlm.nih.gov/pubmed/31722194 http://dx.doi.org/10.1016/j.celrep.2019.10.008 |
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