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Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin pathway plays critical roles in regulating embryonic development and physiological processes. This pathway is tightly regulated to ensure its proper activity. In the absence of Wnt ligands, β-catenin is degraded by...

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Detalles Bibliográficos
Autores principales:	Nguyen, Vu Hong Loan, Hough, Rebecca, Bernaudo, Stefanie, Peng, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905042/ https://www.ncbi.nlm.nih.gov/pubmed/31829231 http://dx.doi.org/10.1186/s13048-019-0596-z

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