Reporter gene-engineering of human induced pluripotent stem cells during differentiation renders in vivo traceable hepatocyte-like cells accessible

Primary hepatocyte transplantation (HTx) is a safe cell therapy for patients with liver disease, but wider application is circumvented by poor cell engraftment due to limitations in hepatocyte quality and transplantation strategies. Hepatocyte-like cells (HLCs) derived from human induced pluripotent...

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Detalles Bibliográficos
Autores principales: Ashmore-Harris, Candice, Blackford, Samuel JI, Grimsdell, Benjamin, Kurtys, Ewelina, Glatz, Marlies C, Rashid, Tamir S, Fruhwirth, Gilbert O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905152/
https://www.ncbi.nlm.nih.gov/pubmed/31707210
http://dx.doi.org/10.1016/j.scr.2019.101599

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