The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers

An ancestral inversion of 900 kb on chromosome 17q21, which includes the microtubule-associated protein tau (MAPT) gene, defines two haplotype clades in Caucasians (H1 and H2). The H1 haplotype has been linked inconsistently with AD. In a previous study, we showed that an SNP tagging this haplotype...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez-Juan, Pascual, Moreno, Sonia, de Rojas, Itziar, Hernández, Isabel, Valero, Sergi, Alegret, Montse, Montrreal, Laura, García González, Pablo, Lage, Carmen, López-García, Sara, Rodrííguez-Rodríguez, Eloy, Orellana, Adelina, Tárraga, Lluís, Boada, Mercè, Ruiz, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905227/
https://www.ncbi.nlm.nih.gov/pubmed/31866851
http://dx.doi.org/10.3389/fnagi.2019.00327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905227/
https://www.ncbi.nlm.nih.gov/pubmed/31866851
http://dx.doi.org/10.3389/fnagi.2019.00327

Ejemplares similares