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The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers

An ancestral inversion of 900 kb on chromosome 17q21, which includes the microtubule-associated protein tau (MAPT) gene, defines two haplotype clades in Caucasians (H1 and H2). The H1 haplotype has been linked inconsistently with AD. In a previous study, we showed that an SNP tagging this haplotype...

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Detalles Bibliográficos
Autores principales:	Sánchez-Juan, Pascual, Moreno, Sonia, de Rojas, Itziar, Hernández, Isabel, Valero, Sergi, Alegret, Montse, Montrreal, Laura, García González, Pablo, Lage, Carmen, López-García, Sara, Rodrííguez-Rodríguez, Eloy, Orellana, Adelina, Tárraga, Lluís, Boada, Mercè, Ruiz, Agustín
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905227/ https://www.ncbi.nlm.nih.gov/pubmed/31866851 http://dx.doi.org/10.3389/fnagi.2019.00327

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