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Water Soluble G-protein Coupled Receptor Enabled Biosensors

This article will briefly overview our efforts in the engineering of water soluble variants of a G-protein coupled receptor (GPCR) and its novel applications to develop biosensors using such water soluble variants of GPCR. While the technologies using water soluble GPCR are still under development,...

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Detalles Bibliográficos
Autores principales: Liu, Renyu, Johnson, A. T. Charlie, Saven, Jeffery G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905389/
https://www.ncbi.nlm.nih.gov/pubmed/31828182
http://dx.doi.org/10.31480/2330-4871/095
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author Liu, Renyu
Johnson, A. T. Charlie
Saven, Jeffery G.
author_facet Liu, Renyu
Johnson, A. T. Charlie
Saven, Jeffery G.
author_sort Liu, Renyu
collection PubMed
description This article will briefly overview our efforts in the engineering of water soluble variants of a G-protein coupled receptor (GPCR) and its novel applications to develop biosensors using such water soluble variants of GPCR. While the technologies using water soluble GPCR are still under development, they offer new tools and strategies to study the function of GPCR, explore potential new compounds for potential clinical usage, and monitor endogenous peptides in various physiological and pathological conditions.
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spelling pubmed-69053892019-12-11 Water Soluble G-protein Coupled Receptor Enabled Biosensors Liu, Renyu Johnson, A. T. Charlie Saven, Jeffery G. Transl Perioper Pain Med Article This article will briefly overview our efforts in the engineering of water soluble variants of a G-protein coupled receptor (GPCR) and its novel applications to develop biosensors using such water soluble variants of GPCR. While the technologies using water soluble GPCR are still under development, they offer new tools and strategies to study the function of GPCR, explore potential new compounds for potential clinical usage, and monitor endogenous peptides in various physiological and pathological conditions. 2019-08-13 2019 /pmc/articles/PMC6905389/ /pubmed/31828182 http://dx.doi.org/10.31480/2330-4871/095 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Liu, Renyu
Johnson, A. T. Charlie
Saven, Jeffery G.
Water Soluble G-protein Coupled Receptor Enabled Biosensors
title Water Soluble G-protein Coupled Receptor Enabled Biosensors
title_full Water Soluble G-protein Coupled Receptor Enabled Biosensors
title_fullStr Water Soluble G-protein Coupled Receptor Enabled Biosensors
title_full_unstemmed Water Soluble G-protein Coupled Receptor Enabled Biosensors
title_short Water Soluble G-protein Coupled Receptor Enabled Biosensors
title_sort water soluble g-protein coupled receptor enabled biosensors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905389/
https://www.ncbi.nlm.nih.gov/pubmed/31828182
http://dx.doi.org/10.31480/2330-4871/095
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