Cargando…
m(6)A minimally impacts the structure, dynamics, and Rev ARM binding properties of HIV-1 RRE stem IIB
N(6)-methyladenosine (m(6)A) is a ubiquitous RNA post-transcriptional modification found in coding as well as non-coding RNAs. m(6)A has also been found in viral RNAs where it is proposed to modulate host-pathogen interactions. Two m(6)A sites have been reported in the HIV-1 Rev response element (RR...
Autores principales: | Chu, Chia-Chieh, Liu, Bei, Plangger, Raphael, Kreutz, Christoph, Al-Hashimi, Hashim M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905585/ https://www.ncbi.nlm.nih.gov/pubmed/31825959 http://dx.doi.org/10.1371/journal.pone.0224850 |
Ejemplares similares
-
Dynamic ensemble of HIV-1 RRE stem IIB reveals non-native conformations that disrupt the Rev-binding site
por: Chu, Chia-Chieh, et al.
Publicado: (2019) -
Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA
por: Schneeberger, Eva-Maria, et al.
Publicado: (2020) -
HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective
por: Rausch, Jason W., et al.
Publicado: (2015) -
Specificity of RSG-1.2 Peptide Binding to RRE-IIB RNA Element of HIV-1 over Rev Peptide Is Mainly Enthalpic in Origin
por: Kumar, Santosh, et al.
Publicado: (2011) -
HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
por: Dzhivhuho, Godfrey, et al.
Publicado: (2022)