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Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4(+) T cell memory

Laboratory mice develop populations of circulating memory CD4(+) T cells in the absence of overt infection. We have previously shown that these populations are replenished from naive precursors at high levels throughout life (Gossel et al., 2017). However, the nature, relative importance and timing...

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Detalles Bibliográficos
Autores principales: Hogan, Thea, Nowicka, Maria, Cownden, Daniel, Pearson, Claire F, Yates, Andrew J, Seddon, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905650/
https://www.ncbi.nlm.nih.gov/pubmed/31742553
http://dx.doi.org/10.7554/eLife.48901

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