Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112

Mycobacterium tuberculosis (Mtb) is able to persist in the body through months of multi‐drug therapy. Mycobacteria possess a wide range of regulatory proteins, including the protein kinase B (PknB) which controls peptidoglycan biosynthesis during growth. Here, we observed that depletion of PknB resu...

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Detalles Bibliográficos
Autores principales: Alqaseer, Kawther, Turapov, Obolbek, Barthe, Philippe, Jagatia, Heena, De Visch, Angélique, Roumestand, Christian, Wegrzyn, Malgorzata, Bartek, Iona L., Voskuil, Martin I., O'Hare, Helen M., Ajuh, Paul, Bottrill, Andrew R., Witney, Adam A., Cohen‐Gonsaud, Martin, Waddell, Simon J., Mukamolova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906086/
https://www.ncbi.nlm.nih.gov/pubmed/31562654
http://dx.doi.org/10.1111/mmi.14398

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