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A Case Series of Fetal Valproate Syndrome in the Republic of Crimea

Valproic acid or valproate is a well-recognized potent teratogen. Antenatal exposure to this drug can cause fetal valproate syndrome (FVS), which is a constellation of distinctive dysmorphic features and congenital malformations. Despite an abundance of reports and registries about this syndrome, th...

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Detalles Bibliográficos
Autores principales: Rybalko, Olga Nikolaevna, Kaladze, Nikolai Nikolaevich, Sukhareva, Irina Alexandrovna, Khoo, Ching Soong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906093/
https://www.ncbi.nlm.nih.gov/pubmed/31831992
http://dx.doi.org/10.1055/s-0039-1700599
Descripción
Sumario:Valproic acid or valproate is a well-recognized potent teratogen. Antenatal exposure to this drug can cause fetal valproate syndrome (FVS), which is a constellation of distinctive dysmorphic features and congenital malformations. Despite an abundance of reports and registries about this syndrome, there is lack of information from Russia, in particular, the Republic of Crimea. We herein describe two cases of FVS from our registry.