A Case Series of Fetal Valproate Syndrome in the Republic of Crimea

Valproic acid or valproate is a well-recognized potent teratogen. Antenatal exposure to this drug can cause fetal valproate syndrome (FVS), which is a constellation of distinctive dysmorphic features and congenital malformations. Despite an abundance of reports and registries about this syndrome, th...

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Autores principales: Rybalko, Olga Nikolaevna, Kaladze, Nikolai Nikolaevich, Sukhareva, Irina Alexandrovna, Khoo, Ching Soong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906093/
https://www.ncbi.nlm.nih.gov/pubmed/31831992
http://dx.doi.org/10.1055/s-0039-1700599
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author Rybalko, Olga Nikolaevna
Kaladze, Nikolai Nikolaevich
Sukhareva, Irina Alexandrovna
Khoo, Ching Soong
author_facet Rybalko, Olga Nikolaevna
Kaladze, Nikolai Nikolaevich
Sukhareva, Irina Alexandrovna
Khoo, Ching Soong
author_sort Rybalko, Olga Nikolaevna
collection PubMed
description Valproic acid or valproate is a well-recognized potent teratogen. Antenatal exposure to this drug can cause fetal valproate syndrome (FVS), which is a constellation of distinctive dysmorphic features and congenital malformations. Despite an abundance of reports and registries about this syndrome, there is lack of information from Russia, in particular, the Republic of Crimea. We herein describe two cases of FVS from our registry.
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spelling pubmed-69060932019-12-12 A Case Series of Fetal Valproate Syndrome in the Republic of Crimea Rybalko, Olga Nikolaevna Kaladze, Nikolai Nikolaevich Sukhareva, Irina Alexandrovna Khoo, Ching Soong J Neurosci Rural Pract Valproic acid or valproate is a well-recognized potent teratogen. Antenatal exposure to this drug can cause fetal valproate syndrome (FVS), which is a constellation of distinctive dysmorphic features and congenital malformations. Despite an abundance of reports and registries about this syndrome, there is lack of information from Russia, in particular, the Republic of Crimea. We herein describe two cases of FVS from our registry. Thieme Medical and Scientific Publishers 2019-10 2019-11-06 /pmc/articles/PMC6906093/ /pubmed/31831992 http://dx.doi.org/10.1055/s-0039-1700599 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Rybalko, Olga Nikolaevna
Kaladze, Nikolai Nikolaevich
Sukhareva, Irina Alexandrovna
Khoo, Ching Soong
A Case Series of Fetal Valproate Syndrome in the Republic of Crimea
title A Case Series of Fetal Valproate Syndrome in the Republic of Crimea
title_full A Case Series of Fetal Valproate Syndrome in the Republic of Crimea
title_fullStr A Case Series of Fetal Valproate Syndrome in the Republic of Crimea
title_full_unstemmed A Case Series of Fetal Valproate Syndrome in the Republic of Crimea
title_short A Case Series of Fetal Valproate Syndrome in the Republic of Crimea
title_sort case series of fetal valproate syndrome in the republic of crimea
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906093/
https://www.ncbi.nlm.nih.gov/pubmed/31831992
http://dx.doi.org/10.1055/s-0039-1700599
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