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Frequencies of clinically important CYP2C19 and CYP2D6 alleles are graded across Europe
CYP2C19 and CYP2D6 are important drug-metabolizing enzymes that are involved in the metabolism of around 30% of all medications. Importantly, the corresponding genes are highly polymorphic and these genetic differences contribute to interindividual and interethnic differences in drug pharmacokinetic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906321/ https://www.ncbi.nlm.nih.gov/pubmed/31358955 http://dx.doi.org/10.1038/s41431-019-0480-8 |