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T cell fate following Salmonella infection is determined by a STING-IRF1 signaling axis in mice

The innate immune response following infection with entero-invasive bacterial species is triggered upon release of cyclic di-guanylate monophosphate (c-di-GMP) into the host cell cytosol. Bacterial c-di-GMP activates the intracellular Sensor Stimulator of Interferon Genes (STING), encoded by Tmem173...

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Detalles Bibliográficos
Autores principales: Park, Sung-Moo, Omatsu, Tatsushi, Zhao, Yun, Yoshida, Naohiro, Shah, Pankaj, Zagani, Rachid, Reinecker, Hans-Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906324/
https://www.ncbi.nlm.nih.gov/pubmed/31840109
http://dx.doi.org/10.1038/s42003-019-0701-2

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