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Differential remodeling of the electron transport chain is required to support TLR3 and TLR4 signaling and cytokine production in macrophages

Increasing evidence suggests that mitochondria play a critical role in driving innate immune responses against bacteria and viruses. However, it is unclear if differential reprogramming of mitochondrial function contributes to the fine tuning of pathogen specific immune responses. Here, we found tha...

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Detalles Bibliográficos
Autores principales: Ahmed, Duale, Roy, David, Jaworski, Allison, Edwards, Alexander, Abizaid, Alfonso, Kumar, Ashok, Golshani, Ashkan, Cassol, Edana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906364/
https://www.ncbi.nlm.nih.gov/pubmed/31827178
http://dx.doi.org/10.1038/s41598-019-55295-4