Limited antibody specificity compromises epitranscriptomic analyses

A controversial discussion on the occurrence of the RNA modification m(1)A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.

Detalles Bibliográficos
Autores principales: Helm, Mark, Lyko, Frank, Motorin, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906430/
https://www.ncbi.nlm.nih.gov/pubmed/31827101
http://dx.doi.org/10.1038/s41467-019-13684-3
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author Helm, Mark
Lyko, Frank
Motorin, Yuri
author_facet Helm, Mark
Lyko, Frank
Motorin, Yuri
author_sort Helm, Mark
collection PubMed
description A controversial discussion on the occurrence of the RNA modification m(1)A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.
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spelling pubmed-69064302019-12-13 Limited antibody specificity compromises epitranscriptomic analyses Helm, Mark Lyko, Frank Motorin, Yuri Nat Commun Comment A controversial discussion on the occurrence of the RNA modification m(1)A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures. Nature Publishing Group UK 2019-12-11 /pmc/articles/PMC6906430/ /pubmed/31827101 http://dx.doi.org/10.1038/s41467-019-13684-3 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Comment
Helm, Mark
Lyko, Frank
Motorin, Yuri
Limited antibody specificity compromises epitranscriptomic analyses
title Limited antibody specificity compromises epitranscriptomic analyses
title_full Limited antibody specificity compromises epitranscriptomic analyses
title_fullStr Limited antibody specificity compromises epitranscriptomic analyses
title_full_unstemmed Limited antibody specificity compromises epitranscriptomic analyses
title_short Limited antibody specificity compromises epitranscriptomic analyses
title_sort limited antibody specificity compromises epitranscriptomic analyses
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906430/
https://www.ncbi.nlm.nih.gov/pubmed/31827101
http://dx.doi.org/10.1038/s41467-019-13684-3
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AT motorinyuri limitedantibodyspecificitycompromisesepitranscriptomicanalyses

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