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Limited antibody specificity compromises epitranscriptomic analyses
A controversial discussion on the occurrence of the RNA modification m(1)A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.
Autores principales: | Helm, Mark, Lyko, Frank, Motorin, Yuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906430/ https://www.ncbi.nlm.nih.gov/pubmed/31827101 http://dx.doi.org/10.1038/s41467-019-13684-3 |
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