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Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer

The mechanisms linking chronic inflammation of the gut (IBD) and increased colorectal cancer susceptibility are poorly understood. IBD risk is influenced by genetic factors, including the IBD5 locus (human 5q31), that harbors the IRF1 gene. A cause-to-effect relationship between chronic inflammation...

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Detalles Bibliográficos
Autores principales:	Jeyakumar, Thiviya, Fodil, Nassima, Van Der Kraak, Lauren, Meunier, Charles, Cayrol, Romain, McGregor, Kevin, Langlais, David, Greenwood, Celia M. T., Beauchemin, Nicole, Gros, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906452/ https://www.ncbi.nlm.nih.gov/pubmed/31827213 http://dx.doi.org/10.1038/s41598-019-55378-2

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