Transcription factor NFAT5 contributes to the glycolytic phenotype rewiring and pancreatic cancer progression via transcription of PGK1

Hypoxia and the hypovascular tumor microenvironment are major hallmarks of pancreatic ductal adenocarcinoma (PDAC), in which glycolysis is of great importance to tumor survival and proliferation. There is little research regarding the role of Nuclear Factor of Activated T Cells 5 (NFAT5) in relation...

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Detalles Bibliográficos
Autores principales: Jiang, Yongsheng, He, Ruizhe, Jiang, Yuhong, Liu, Dejun, Tao, Lingye, Yang, Minwei, Lin, Chaoyi, Shen, Yang, Fu, Xueliang, Yang, Jianyu, Li, Jiao, Huo, Yanmiao, Hua, Rong, Liu, Wei, Zhang, Junfeng, Shen, Baiyong, Zhang, Zhigang, Sun, Yongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906509/
https://www.ncbi.nlm.nih.gov/pubmed/31827081
http://dx.doi.org/10.1038/s41419-019-2072-5

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