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The use of genetically humanized animal models for personalized medicine approaches
For many genetic diseases, researchers are developing personalized medicine approaches. These sometimes employ custom genetic interventions such as antisense-mediated exon skipping or genome editing, aiming to restore protein function in a mutation-specific manner. Animal models can facilitate the d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906630/ https://www.ncbi.nlm.nih.gov/pubmed/31591145 http://dx.doi.org/10.1242/dmm.041673 |