De novo biosynthesis of 8-hydroxyoctanoic acid via a medium-chain length specific fatty acid synthase and cytochrome P450 in Saccharomyces cerevisiae

Terminally hydroxylated fatty acids or dicarboxylic acids are industrially relevant compounds with broad applications. Here, we present the proof of principle for the de novo biosynthesis of 8-hydroxyoctanoic acid from glucose and ethanol in the yeast Saccharomyces cerevisiae. Toxicity tests with me...

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Detalles Bibliográficos
Autores principales: Wernig, Florian, Boles, Eckhard, Oreb, Mislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906673/
https://www.ncbi.nlm.nih.gov/pubmed/31867212
http://dx.doi.org/10.1016/j.mec.2019.e00111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906673/
https://www.ncbi.nlm.nih.gov/pubmed/31867212
http://dx.doi.org/10.1016/j.mec.2019.e00111

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