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Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States

OBJECTIVE: To examine the trends, characteristics, and outcomes of women with gynecologic malignancies who died of suicide in the United States. METHODS: This is a retrospective, observational study using the Surveillance, Epidemiology and End Results program from 1973 to 2013. Women with uterine, o...

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Autores principales: Violette, Caroline J., Mandelbaum, Rachel S., Nusbaum, David J., Duval, Christina J., Matsuzaki, Shinya, Machida, Hiroko, Roman, Lynda D., Matsuo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906713/
https://www.ncbi.nlm.nih.gov/pubmed/31867431
http://dx.doi.org/10.1016/j.gore.2019.100510
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author Violette, Caroline J.
Mandelbaum, Rachel S.
Nusbaum, David J.
Duval, Christina J.
Matsuzaki, Shinya
Machida, Hiroko
Roman, Lynda D.
Matsuo, Koji
author_facet Violette, Caroline J.
Mandelbaum, Rachel S.
Nusbaum, David J.
Duval, Christina J.
Matsuzaki, Shinya
Machida, Hiroko
Roman, Lynda D.
Matsuo, Koji
author_sort Violette, Caroline J.
collection PubMed
description OBJECTIVE: To examine the trends, characteristics, and outcomes of women with gynecologic malignancies who died of suicide in the United States. METHODS: This is a retrospective, observational study using the Surveillance, Epidemiology and End Results program from 1973 to 2013. Women with uterine, ovarian, and cervical cancers who had cause of death recorded as suicide or self-inflicted injury were included, and temporal trends, patient and tumor characteristics, and outcomes were assessed. RESULTS: Of 467,368 women with gynecologic cancers, there were 309 (0.07%) suicides during the study period. Across the three malignancies, suicide rates significantly decreased during the study period, with uterine cancer exhibiting the highest interval decrease (relative reduction: uterine cancer 88.2%, cervical cancer 78.1%, and ovarian cancer 73.6%; all, P < 0.05). Women with cervical cancer were younger at age of suicide (median age, 50 versus 60–68 years), and women with ovarian cancer had a shorter time to suicide from diagnosis (median time, 27 versus 66–67 months) (both, P < 0.05). On multivariable analysis, white race (hazard ratio [HR] 3.619), Western U.S. residence (HR 2.012), ovarian cancer (HR 1.991), cervical cancer (HR 1.765), stage IV disease (HR 1.735), and divorced status (HR 1.491) remained independent clinico-pathological characteristics associated with increased risk of suicide (all, P < 0.05). CONCLUSION: This study found that suicide rates in women with gynecologic malignancies have decreased in the United States. Characteristics of suicide vary across cancer types, and certain risk factors of suicide identified in this study may be useful to triage patients at risk for suicidal behavior and inform prevention strategies.
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spelling pubmed-69067132019-12-20 Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States Violette, Caroline J. Mandelbaum, Rachel S. Nusbaum, David J. Duval, Christina J. Matsuzaki, Shinya Machida, Hiroko Roman, Lynda D. Matsuo, Koji Gynecol Oncol Rep Case Series OBJECTIVE: To examine the trends, characteristics, and outcomes of women with gynecologic malignancies who died of suicide in the United States. METHODS: This is a retrospective, observational study using the Surveillance, Epidemiology and End Results program from 1973 to 2013. Women with uterine, ovarian, and cervical cancers who had cause of death recorded as suicide or self-inflicted injury were included, and temporal trends, patient and tumor characteristics, and outcomes were assessed. RESULTS: Of 467,368 women with gynecologic cancers, there were 309 (0.07%) suicides during the study period. Across the three malignancies, suicide rates significantly decreased during the study period, with uterine cancer exhibiting the highest interval decrease (relative reduction: uterine cancer 88.2%, cervical cancer 78.1%, and ovarian cancer 73.6%; all, P < 0.05). Women with cervical cancer were younger at age of suicide (median age, 50 versus 60–68 years), and women with ovarian cancer had a shorter time to suicide from diagnosis (median time, 27 versus 66–67 months) (both, P < 0.05). On multivariable analysis, white race (hazard ratio [HR] 3.619), Western U.S. residence (HR 2.012), ovarian cancer (HR 1.991), cervical cancer (HR 1.765), stage IV disease (HR 1.735), and divorced status (HR 1.491) remained independent clinico-pathological characteristics associated with increased risk of suicide (all, P < 0.05). CONCLUSION: This study found that suicide rates in women with gynecologic malignancies have decreased in the United States. Characteristics of suicide vary across cancer types, and certain risk factors of suicide identified in this study may be useful to triage patients at risk for suicidal behavior and inform prevention strategies. Elsevier 2019-10-24 /pmc/articles/PMC6906713/ /pubmed/31867431 http://dx.doi.org/10.1016/j.gore.2019.100510 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Series
Violette, Caroline J.
Mandelbaum, Rachel S.
Nusbaum, David J.
Duval, Christina J.
Matsuzaki, Shinya
Machida, Hiroko
Roman, Lynda D.
Matsuo, Koji
Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States
title Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States
title_full Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States
title_fullStr Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States
title_full_unstemmed Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States
title_short Temporal trends and characteristics of suicide among women with gynecologic malignancy in the United States
title_sort temporal trends and characteristics of suicide among women with gynecologic malignancy in the united states
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906713/
https://www.ncbi.nlm.nih.gov/pubmed/31867431
http://dx.doi.org/10.1016/j.gore.2019.100510
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