Ifenprodil and Flavopiridol Identified by Genomewide RNA Interference Screening as Effective Drugs To Ameliorate Murine Acute Lung Injury after Influenza A H5N1 Virus Infection

Due to the limitations of effective treatments, avian influenza A H5N1 virus is the most lethal influenza virus strain that causes severe acute lung injury (ALI). To develop effective drugs ameliorating H5N1-induced ALI, we explore an RNA interference (RNAi) screening method to monitor changes in ce...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Zhang, Yuqing, Qin, Yuhao, Zhang, Qingchao, Liu, Qiang, Shang, Daozhen, Lu, Huijun, Li, Xiao, Zhou, Congzhao, Huang, Fengming, Jin, Ningyi, Jiang, Chengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906739/
https://www.ncbi.nlm.nih.gov/pubmed/31822599
http://dx.doi.org/10.1128/mSystems.00431-19

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