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Carbohydrate Modifications of Neoandrographolide for Improved Reactive Oxygen Species-Mediated Apoptosis through Mitochondrial Pathway in Colon Cancer
[Image: see text] Modifications at the carbohydrate moiety of neoandrographolide, isolated from the medicinal plant Andrographis paniculata, result in more potent and less toxic derivatives, namely, 4′,6′-benzylidene neoandrographolide (2b) and 4′6′-p-methoxybenzylidene neoandrographolide (2c). Thes...
Autores principales: | Sharma, Venu, Qayum, Arem, Kaul, Sanjana, Singh, Ajeet, Kapoor, Kamal K., Mukherjee, Debaraj, Singh, Shashank K., Dhar, Manoj K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906770/ https://www.ncbi.nlm.nih.gov/pubmed/31858026 http://dx.doi.org/10.1021/acsomega.9b01249 |
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