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Medical Application of Hydrogen in Hematological Diseases

Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative...

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Detalles Bibliográficos
Autores principales: Qian, Liren, Wu, Zhengcheng, Cen, Jian, Pasca, Sergiu, Tomuleasa, Ciprian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906850/
https://www.ncbi.nlm.nih.gov/pubmed/31871547
http://dx.doi.org/10.1155/2019/3917393
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author Qian, Liren
Wu, Zhengcheng
Cen, Jian
Pasca, Sergiu
Tomuleasa, Ciprian
author_facet Qian, Liren
Wu, Zhengcheng
Cen, Jian
Pasca, Sergiu
Tomuleasa, Ciprian
author_sort Qian, Liren
collection PubMed
description Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative, anti-inflammatory, and antiapoptotic effects. In the past two decades, more than 1000 papers have been published on the topic, including organ ischemia-reperfusion injury, radiation injury, diabetes, atherosclerosis, hypertension, or cancer. We have previously hypothesized and proven the therapeutic effects of hydrogen gas in graft-versus-host disease following stem cell transplantation. In the current manuscript, we present the clinical advances of hydrogen gas in hematological disorders.
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spelling pubmed-69068502019-12-23 Medical Application of Hydrogen in Hematological Diseases Qian, Liren Wu, Zhengcheng Cen, Jian Pasca, Sergiu Tomuleasa, Ciprian Oxid Med Cell Longev Review Article Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative, anti-inflammatory, and antiapoptotic effects. In the past two decades, more than 1000 papers have been published on the topic, including organ ischemia-reperfusion injury, radiation injury, diabetes, atherosclerosis, hypertension, or cancer. We have previously hypothesized and proven the therapeutic effects of hydrogen gas in graft-versus-host disease following stem cell transplantation. In the current manuscript, we present the clinical advances of hydrogen gas in hematological disorders. Hindawi 2019-11-28 /pmc/articles/PMC6906850/ /pubmed/31871547 http://dx.doi.org/10.1155/2019/3917393 Text en Copyright © 2019 Liren Qian et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Qian, Liren
Wu, Zhengcheng
Cen, Jian
Pasca, Sergiu
Tomuleasa, Ciprian
Medical Application of Hydrogen in Hematological Diseases
title Medical Application of Hydrogen in Hematological Diseases
title_full Medical Application of Hydrogen in Hematological Diseases
title_fullStr Medical Application of Hydrogen in Hematological Diseases
title_full_unstemmed Medical Application of Hydrogen in Hematological Diseases
title_short Medical Application of Hydrogen in Hematological Diseases
title_sort medical application of hydrogen in hematological diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906850/
https://www.ncbi.nlm.nih.gov/pubmed/31871547
http://dx.doi.org/10.1155/2019/3917393
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