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Medical Application of Hydrogen in Hematological Diseases
Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906850/ https://www.ncbi.nlm.nih.gov/pubmed/31871547 http://dx.doi.org/10.1155/2019/3917393 |
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author | Qian, Liren Wu, Zhengcheng Cen, Jian Pasca, Sergiu Tomuleasa, Ciprian |
author_facet | Qian, Liren Wu, Zhengcheng Cen, Jian Pasca, Sergiu Tomuleasa, Ciprian |
author_sort | Qian, Liren |
collection | PubMed |
description | Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative, anti-inflammatory, and antiapoptotic effects. In the past two decades, more than 1000 papers have been published on the topic, including organ ischemia-reperfusion injury, radiation injury, diabetes, atherosclerosis, hypertension, or cancer. We have previously hypothesized and proven the therapeutic effects of hydrogen gas in graft-versus-host disease following stem cell transplantation. In the current manuscript, we present the clinical advances of hydrogen gas in hematological disorders. |
format | Online Article Text |
id | pubmed-6906850 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-69068502019-12-23 Medical Application of Hydrogen in Hematological Diseases Qian, Liren Wu, Zhengcheng Cen, Jian Pasca, Sergiu Tomuleasa, Ciprian Oxid Med Cell Longev Review Article Hydrogen gas has been reported to have medical efficacy since the 1880s. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative, anti-inflammatory, and antiapoptotic effects. In the past two decades, more than 1000 papers have been published on the topic, including organ ischemia-reperfusion injury, radiation injury, diabetes, atherosclerosis, hypertension, or cancer. We have previously hypothesized and proven the therapeutic effects of hydrogen gas in graft-versus-host disease following stem cell transplantation. In the current manuscript, we present the clinical advances of hydrogen gas in hematological disorders. Hindawi 2019-11-28 /pmc/articles/PMC6906850/ /pubmed/31871547 http://dx.doi.org/10.1155/2019/3917393 Text en Copyright © 2019 Liren Qian et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Qian, Liren Wu, Zhengcheng Cen, Jian Pasca, Sergiu Tomuleasa, Ciprian Medical Application of Hydrogen in Hematological Diseases |
title | Medical Application of Hydrogen in Hematological Diseases |
title_full | Medical Application of Hydrogen in Hematological Diseases |
title_fullStr | Medical Application of Hydrogen in Hematological Diseases |
title_full_unstemmed | Medical Application of Hydrogen in Hematological Diseases |
title_short | Medical Application of Hydrogen in Hematological Diseases |
title_sort | medical application of hydrogen in hematological diseases |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906850/ https://www.ncbi.nlm.nih.gov/pubmed/31871547 http://dx.doi.org/10.1155/2019/3917393 |
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