Artemether Activation of AMPK/GSK3β(ser9)/Nrf2 Signaling Confers Neuroprotection towards β-Amyloid-Induced Neurotoxicity in 3xTg Alzheimer's Mouse Model

Alzheimer's disease is a severe neurodegenerative disease. Multiple factors involving neurofibrillary tangles and amyloid-β plaques lead to the progression of the AD, generated by aggregated hyperphosphorylated Tau protein. Inflammation, mitochondrial dysfunction, and oxidative stress play a si...

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Detalles Bibliográficos
Autores principales: Li, Shuai, Zhao, Xia, Lazarovici, Philip, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907052/
https://www.ncbi.nlm.nih.gov/pubmed/31871541
http://dx.doi.org/10.1155/2019/1862437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907052/
https://www.ncbi.nlm.nih.gov/pubmed/31871541
http://dx.doi.org/10.1155/2019/1862437

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