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The Herb-Drug Pharmacokinetic Interaction of Fluoxetine and Its Metabolite Norfluoxetine with a Traditional Chinese Medicine in Rats by LC-MS/MS

BACKGROUND: Fluoxetine (FLU) is the first-line and widely used medication for depression. The combination of Chaihu Shugan san (CSGS) and FLU is commonly used to enhance antidepressant effects and reduce side effects. OBJECTIVE: The primary objective of this study was to investigate the potential ph...

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Detalles Bibliográficos
Autores principales:	Yan, Lijing, Wang, Sheng, Zhao, Linlin, Qiu, Juan, Zhou, Lu, Wang, Wenbo, Xu, Xia, Wang, Dongsheng, Qiu, Xinjian, Qin, Dilan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907063/ https://www.ncbi.nlm.nih.gov/pubmed/31871472 http://dx.doi.org/10.1155/2019/2471870

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