Intrastriatal Memantine Infusion Dampens Levodopa-Induced Dyskinesia and Motor Deficits in a Mouse Model of Hemiparkinsonism

Although the administration of dopamine precursor levodopa remains as the mainstay for the treatment of Parkinson's disease, long-term exposure to levodopa often causes a disabling complication, referred to as levodopa-induced dyskinesias. Therefore, the development of new therapeutic intervent...

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Detalles Bibliográficos
Autores principales: Ogawa, Masatoshi, Zhou, Yu, Tsuji, Ryosuke, Kasahara, Jiro, Goto, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907096/
https://www.ncbi.nlm.nih.gov/pubmed/31866925
http://dx.doi.org/10.3389/fneur.2019.01258

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