Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy

BACKGROUND: Clinical application of cancer immunotherapy requires a better understanding of tumor immunogenicity and the tumor microenvironment. HLA class I molecules present antigens to CD8(+) cytotoxic cells. Their loss or downregulation is frequently found in tumors resulting in reduced T cell re...

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Detalles Bibliográficos
Autores principales: Sinn, Bruno Valentin, Weber, Karsten E., Schmitt, Wolfgang Daniel, Fasching, Peter A., Symmans, William Fraser, Blohmer, Jens-Uwe, Karn, Thomas, Taube, Eliane Tabea, Klauschen, Frederick, Marmé, Frederik, Schem, Christian, Stickeler, Elmar, Ataseven, Beyhan, Huober, Jens, von Minckwitz, Gunter, Seliger, Barbara, Denkert, Carsten, Loibl, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907189/
https://www.ncbi.nlm.nih.gov/pubmed/31829264
http://dx.doi.org/10.1186/s13058-019-1231-z

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