Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model

BACKGROUND: Members of the HMGN protein family modulate chromatin structure and influence epigenetic modifications. HMGN1 and HMGN2 are highly expressed during early development and in the neural stem/progenitor cells of the developing and adult brain. Here, we investigate whether HMGN proteins cont...

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Detalles Bibliográficos
Autores principales: Garza-Manero, Sylvia, Sindi, Abdulmajeed Abdulghani A., Mohan, Gokula, Rehbini, Ohoud, Jeantet, Valentine H. M., Bailo, Mariarca, Latif, Faeezah Abdul, West, Maureen P., Gurden, Ross, Finlayson, Lauren, Svambaryte, Silvija, West, Adam G., West, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907237/
https://www.ncbi.nlm.nih.gov/pubmed/31831052
http://dx.doi.org/10.1186/s13072-019-0320-7

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