Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain

Host interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral restriction factors. Of these, IFITM3 potently inhibits viruses that enter cells through acidic endosomes, many of which are zoonotic and emerging viruses with bats (order Chiroptera) as their natural hosts. We prev...

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Detalles Bibliográficos
Autores principales: Benfield, Camilla TO, MacKenzie, Farrell, Ritzefeld, Markus, Mazzon, Michela, Weston, Stuart, Tate, Edward W, Teo, Boon Han, Smith, Sarah E, Kellam, Paul, Holmes, Edward C, Marsh, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907390/
https://www.ncbi.nlm.nih.gov/pubmed/31826928
http://dx.doi.org/10.26508/lsa.201900542

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