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Escherichia coli “TatExpress” strains export several g/L human growth hormone to the periplasm by the Tat pathway
Escherichia coli is a heavily used platform for the production of biotherapeutic and other high‐value proteins, and a favored strategy is to export the protein of interest to the periplasm to simplify downstream processing and facilitate disulfide bond formation. The Sec pathway is the standard mean...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907408/ https://www.ncbi.nlm.nih.gov/pubmed/31429928 http://dx.doi.org/10.1002/bit.27147 |