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Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report

BACKGROUND: Outcome of type 2 diabetes care depends on the acceptance of self-responsibility by informed patients, as treatment goals will otherwise be missed. AIMS AND METHODS: This pre/post-observational report describes the clinical outcome of type 2 diabetes care in patients with type 2 diabetes...

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Autores principales: Haslacher, Helmuth, Fallmann, Hannelore, Waldhäusl, Claudia, Hartmann, Edith, Wagner, Oswald F., Waldhäusl, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907777/
https://www.ncbi.nlm.nih.gov/pubmed/31830073
http://dx.doi.org/10.1371/journal.pone.0226132
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author Haslacher, Helmuth
Fallmann, Hannelore
Waldhäusl, Claudia
Hartmann, Edith
Wagner, Oswald F.
Waldhäusl, Werner
author_facet Haslacher, Helmuth
Fallmann, Hannelore
Waldhäusl, Claudia
Hartmann, Edith
Wagner, Oswald F.
Waldhäusl, Werner
author_sort Haslacher, Helmuth
collection PubMed
description BACKGROUND: Outcome of type 2 diabetes care depends on the acceptance of self-responsibility by informed patients, as treatment goals will otherwise be missed. AIMS AND METHODS: This pre/post-observational report describes the clinical outcome of type 2 diabetes care in patients with type 2 diabetes (N =930) admitted consecutively to a diabetes rehabilitation clinic (DRC) between June 2013, and June 2016, where they were exposed to standardized lifestyle modification with meals low in salt and rich in vegetables and fruits, totaling 1,200 to 1,600 kcal/d, and an add-on exercise load equivalent to 400–600 kcal/d. RESULTS: At admission, patients presented with multiple treatment modes, elevated HbA(1c) levels (7.6±1.5%, 60±16 mmol/mol), a high prevalence of co-morbidities dominated by obesity (79%), a low rate of influenza and pneumococcal immunization (<9%) and underuse of lipid-lowering drugs (-29%). Analysis of clinical and metabolic outcome after 3 weeks shows that simple standardization of and better adherence to treatment recommendations improved (p<0.0001) glucose (HbA(1c) -0.4±0.4%) and lipid metabolism (LDL/HDL ratio, -0.58±0.03), permitting a 39% reduction in insulin dosage, omission of insulin in 36/232 patients and omission of oral antidiabetic drugs (OADs) other than metformin and DPP4-inhibitors, while the use of GLP-1 analogs doubled to 5.2%. Improved outcome was independent of treatment strategy and more marked at initially high HbA(1c) at costs less than 25% of those encountered at a standard hospital. CONCLUSIONS: Our observations support the clinical notion that adherence to basic treatment recommendations is indispensable in type 2 diabetes care if metabolic and clinical treatment goals are to be met, and if inappropriate add-on over-medicalization with OADs and/or insulin is to be avoided. To this end, ‘imprinting’ patients at a DRC could be of considerable help.
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spelling pubmed-69077772019-12-27 Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report Haslacher, Helmuth Fallmann, Hannelore Waldhäusl, Claudia Hartmann, Edith Wagner, Oswald F. Waldhäusl, Werner PLoS One Research Article BACKGROUND: Outcome of type 2 diabetes care depends on the acceptance of self-responsibility by informed patients, as treatment goals will otherwise be missed. AIMS AND METHODS: This pre/post-observational report describes the clinical outcome of type 2 diabetes care in patients with type 2 diabetes (N =930) admitted consecutively to a diabetes rehabilitation clinic (DRC) between June 2013, and June 2016, where they were exposed to standardized lifestyle modification with meals low in salt and rich in vegetables and fruits, totaling 1,200 to 1,600 kcal/d, and an add-on exercise load equivalent to 400–600 kcal/d. RESULTS: At admission, patients presented with multiple treatment modes, elevated HbA(1c) levels (7.6±1.5%, 60±16 mmol/mol), a high prevalence of co-morbidities dominated by obesity (79%), a low rate of influenza and pneumococcal immunization (<9%) and underuse of lipid-lowering drugs (-29%). Analysis of clinical and metabolic outcome after 3 weeks shows that simple standardization of and better adherence to treatment recommendations improved (p<0.0001) glucose (HbA(1c) -0.4±0.4%) and lipid metabolism (LDL/HDL ratio, -0.58±0.03), permitting a 39% reduction in insulin dosage, omission of insulin in 36/232 patients and omission of oral antidiabetic drugs (OADs) other than metformin and DPP4-inhibitors, while the use of GLP-1 analogs doubled to 5.2%. Improved outcome was independent of treatment strategy and more marked at initially high HbA(1c) at costs less than 25% of those encountered at a standard hospital. CONCLUSIONS: Our observations support the clinical notion that adherence to basic treatment recommendations is indispensable in type 2 diabetes care if metabolic and clinical treatment goals are to be met, and if inappropriate add-on over-medicalization with OADs and/or insulin is to be avoided. To this end, ‘imprinting’ patients at a DRC could be of considerable help. Public Library of Science 2019-12-12 /pmc/articles/PMC6907777/ /pubmed/31830073 http://dx.doi.org/10.1371/journal.pone.0226132 Text en © 2019 Haslacher et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Haslacher, Helmuth
Fallmann, Hannelore
Waldhäusl, Claudia
Hartmann, Edith
Wagner, Oswald F.
Waldhäusl, Werner
Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report
title Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report
title_full Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report
title_fullStr Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report
title_full_unstemmed Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report
title_short Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report
title_sort type 2 diabetes care: improvement by standardization at a diabetes rehabilitation clinic. an observational report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907777/
https://www.ncbi.nlm.nih.gov/pubmed/31830073
http://dx.doi.org/10.1371/journal.pone.0226132
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