Reversed metabolic reprogramming as a measure of cancer treatment efficacy in rat C6 glioma model

BACKGROUND: Metabolism in tumor shifts from oxidative phosphorylation to inefficient glycolysis resulting in overproduction of lactate (Warburg effect), and cancers may be effectively treated if this imbalance were corrected. The aim of this longitudinal study of glioblastoma in a rat model was to d...

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Detalles Bibliográficos
Autores principales: Datta, Keshav, Lauritzen, Mette H., Merchant, Milton, Jang, Taichang, Liu, Shie-Chau, Hurd, Ralph, Recht, Lawrence, Spielman, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907781/
https://www.ncbi.nlm.nih.gov/pubmed/31830049
http://dx.doi.org/10.1371/journal.pone.0225313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907781/
https://www.ncbi.nlm.nih.gov/pubmed/31830049
http://dx.doi.org/10.1371/journal.pone.0225313

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