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Reversed metabolic reprogramming as a measure of cancer treatment efficacy in rat C6 glioma model
BACKGROUND: Metabolism in tumor shifts from oxidative phosphorylation to inefficient glycolysis resulting in overproduction of lactate (Warburg effect), and cancers may be effectively treated if this imbalance were corrected. The aim of this longitudinal study of glioblastoma in a rat model was to d...
Autores principales: | Datta, Keshav, Lauritzen, Mette H., Merchant, Milton, Jang, Taichang, Liu, Shie-Chau, Hurd, Ralph, Recht, Lawrence, Spielman, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907781/ https://www.ncbi.nlm.nih.gov/pubmed/31830049 http://dx.doi.org/10.1371/journal.pone.0225313 |
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