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Selective breeding modifies mef2ca mutant incomplete penetrance by tuning the opposing Notch pathway
Deleterious genetic mutations allow developmental biologists to understand how genes control development. However, not all loss of function genetic mutants develop phenotypic changes. Many deleterious mutations only produce a phenotype in a subset of mutant individuals, a phenomenon known as incompl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907857/ https://www.ncbi.nlm.nih.gov/pubmed/31790396 http://dx.doi.org/10.1371/journal.pgen.1008507 |