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A computational study on the role of glutamate and NMDA receptors on cortical spreading depression using a multidomain electrodiffusion model

Cortical spreading depression (SD) is a spreading disruption of ionic homeostasis in the brain during which neurons experience complete and prolonged depolarizations. SD is the basis of migraine aura and is increasingly associated with many other brain pathologies. Here, we study the role of glutama...

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Detalles Bibliográficos
Autores principales: Tuttle, Austin, Riera Diaz, Jorge, Mori, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907880/
https://www.ncbi.nlm.nih.gov/pubmed/31790388
http://dx.doi.org/10.1371/journal.pcbi.1007455