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Discovery of Novel Small Molecules that Block Myofibroblast Formation: Implications for Capsular Contracture Treatment

Capsular contracture is a devastating complication that occurs in patients undergoing implant-based breast reconstruction. Ionizing radiation drives and exacerbates capsular contracture in part by activating cytokines, including transforming growth factor-beta (TGF-β). TGF-β promotes myofibroblast d...

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Detalles Bibliográficos
Autores principales:	Park, Rachel H., Pollock, Stephen J., Phipps, Richard P., Langstein, Howard N., Woeller, Collynn F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2019
Materias:	Experimental
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908376/ https://www.ncbi.nlm.nih.gov/pubmed/31942393 http://dx.doi.org/10.1097/GOX.0000000000002430

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