A Targetron-Recombinase System for Large-Scale Genome Engineering of Clostridia

Clostridia are a group of Gram-positive anaerobic bacteria of medical and industrial importance for which limited genetic methods are available. Here, we demonstrate an approach to make large genomic deletions and insertions in the model Clostridium phytofermentans by combining designed group II int...

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Detalles Bibliográficos
Autores principales: Cerisy, Tristan, Rostain, William, Chhun, Audam, Boutard, Magali, Salanoubat, Marcel, Tolonen, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908422/
https://www.ncbi.nlm.nih.gov/pubmed/31826971
http://dx.doi.org/10.1128/mSphere.00710-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908422/
https://www.ncbi.nlm.nih.gov/pubmed/31826971
http://dx.doi.org/10.1128/mSphere.00710-19

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