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A Targetron-Recombinase System for Large-Scale Genome Engineering of Clostridia
Clostridia are a group of Gram-positive anaerobic bacteria of medical and industrial importance for which limited genetic methods are available. Here, we demonstrate an approach to make large genomic deletions and insertions in the model Clostridium phytofermentans by combining designed group II int...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908422/ https://www.ncbi.nlm.nih.gov/pubmed/31826971 http://dx.doi.org/10.1128/mSphere.00710-19 |