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Targeting Pin1 by All-Trans Retinoic Acid (ATRA) Overcomes Tamoxifen Resistance in Breast Cancer via Multifactorial Mechanisms

Breast cancer is the most prevalent tumor in women worldwide and about 70% patients are estrogen receptor positive. In these cancer patients, resistance to the anticancer estrogen receptor antagonist tamoxifen emerges to be a major clinical obstacle. Peptidyl-prolyl isomerase Pin1 is prominently ove...

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Detalles Bibliográficos
Autores principales:	Huang, Songyin, Chen, Yang, Liang, Zhi-Mei, Li, Na-Na, Liu, Yujie, Zhu, Yinghua, Liao, Dingzhun, Zhou, Xiao Zhen, Lu, Kun Ping, Yao, Yandan, Luo, Man-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908472/ https://www.ncbi.nlm.nih.gov/pubmed/31867329 http://dx.doi.org/10.3389/fcell.2019.00322

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