Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review

Lupus nephritis (LN) in Children is caused by Kidney involvement in systemic lupus erythematosus (SLE). SLE is a chronic, multi-systemic, paroxysmal autoimmune disease with a wide spectrum of autoantibodies. Hypercalcemia is a common manifestation of primary hyperparathyroidism and other malignant t...

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Detalles Bibliográficos
Autores principales: Xu, Lingling, Zhang, Jun, Pu, Ronghui, Yue, Zhihui, Mo, Ying, Jiang, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908478/
https://www.ncbi.nlm.nih.gov/pubmed/31867297
http://dx.doi.org/10.3389/fped.2019.00507
Descripción
Sumario:Lupus nephritis (LN) in Children is caused by Kidney involvement in systemic lupus erythematosus (SLE). SLE is a chronic, multi-systemic, paroxysmal autoimmune disease with a wide spectrum of autoantibodies. Hypercalcemia is a common manifestation of primary hyperparathyroidism and other malignant tumors. LN or SLE with hypercalcemia is rare. We report a case of LN with hypercalcemia and review the literature. It suggests that the pathogenesis of SLE complicated with hypercalcemia complicates the response of drug therapy.

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