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Assessment of brain delivery of a model ABCB1/ABCG2 substrate in patients with non-contrast-enhancing brain tumors with positron emission tomography

BACKGROUND: P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) are two efflux transporters expressed at the blood–brain barrier which effectively restrict the brain distribution of the majority of currently known anticancer drugs. High-grade brain tumors often possess a disrupted bl...

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Detalles Bibliográficos
Autores principales:	Wulkersdorfer, Beatrix, Bauer, Martin, Karch, Rudolf, Stefanits, Harald, Philippe, Cécile, Weber, Maria, Czech, Thomas, Menet, Marie-Claude, Declèves, Xavier, Hainfellner, Johannes A., Preusser, Matthias, Hacker, Marcus, Zeitlinger, Markus, Müller, Markus, Langer, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908538/ https://www.ncbi.nlm.nih.gov/pubmed/31832814 http://dx.doi.org/10.1186/s13550-019-0581-y

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