Cargando…

Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview

Noninvasive imaging modalities offer the possibility to dynamically evaluate cardiac motion during the cardiac cycle by means of ECG-gated acquisitions. Such motion characterization along with orientation, segmentation preprocessing, and ultimately, phase analysis, can provide quantitative estimates...

Descripción completa

Detalles Bibliográficos
Autores principales: Juarez-Orozco, Luis Eduardo, Monroy-Gonzalez, Andrea, Prakken, Niek H. J., Noordzij, Walter, Knuuti, Juhani, deKemp, Robert A., Slart, Riemer H. J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908565/
https://www.ncbi.nlm.nih.gov/pubmed/30834496
http://dx.doi.org/10.1007/s12350-019-01670-7
_version_ 1783478751814746112
author Juarez-Orozco, Luis Eduardo
Monroy-Gonzalez, Andrea
Prakken, Niek H. J.
Noordzij, Walter
Knuuti, Juhani
deKemp, Robert A.
Slart, Riemer H. J. A.
author_facet Juarez-Orozco, Luis Eduardo
Monroy-Gonzalez, Andrea
Prakken, Niek H. J.
Noordzij, Walter
Knuuti, Juhani
deKemp, Robert A.
Slart, Riemer H. J. A.
author_sort Juarez-Orozco, Luis Eduardo
collection PubMed
description Noninvasive imaging modalities offer the possibility to dynamically evaluate cardiac motion during the cardiac cycle by means of ECG-gated acquisitions. Such motion characterization along with orientation, segmentation preprocessing, and ultimately, phase analysis, can provide quantitative estimates of ventricular mechanical synchrony. Current evidence on the role of mechanical synchrony evaluation is mainly available for echocardiography and gated single-photon emission computed tomography, but less is known about the utilization of gated positron emission tomography (PET). Although data available are sparse, there is indication that mechanical synchrony evaluation can be of diagnostic and prognostic values in patients with known or suspected coronary artery disease-related myocardial ischemia, prediction of response to cardiac resynchronization therapy, and estimation of risk for adverse cardiac events in patients’ heart failure. As such, the evaluation of mechanical ventricular synchrony through phase analysis of gated acquisitions represents a value addition to modern cardiac PET imaging modality, which warrants further research and development in the evaluation of patients with cardiovascular disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12350-019-01670-7) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6908565
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-69085652019-12-26 Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview Juarez-Orozco, Luis Eduardo Monroy-Gonzalez, Andrea Prakken, Niek H. J. Noordzij, Walter Knuuti, Juhani deKemp, Robert A. Slart, Riemer H. J. A. J Nucl Cardiol Review Article Noninvasive imaging modalities offer the possibility to dynamically evaluate cardiac motion during the cardiac cycle by means of ECG-gated acquisitions. Such motion characterization along with orientation, segmentation preprocessing, and ultimately, phase analysis, can provide quantitative estimates of ventricular mechanical synchrony. Current evidence on the role of mechanical synchrony evaluation is mainly available for echocardiography and gated single-photon emission computed tomography, but less is known about the utilization of gated positron emission tomography (PET). Although data available are sparse, there is indication that mechanical synchrony evaluation can be of diagnostic and prognostic values in patients with known or suspected coronary artery disease-related myocardial ischemia, prediction of response to cardiac resynchronization therapy, and estimation of risk for adverse cardiac events in patients’ heart failure. As such, the evaluation of mechanical ventricular synchrony through phase analysis of gated acquisitions represents a value addition to modern cardiac PET imaging modality, which warrants further research and development in the evaluation of patients with cardiovascular disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12350-019-01670-7) contains supplementary material, which is available to authorized users. Springer International Publishing 2019-03-04 2019 /pmc/articles/PMC6908565/ /pubmed/30834496 http://dx.doi.org/10.1007/s12350-019-01670-7 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review Article
Juarez-Orozco, Luis Eduardo
Monroy-Gonzalez, Andrea
Prakken, Niek H. J.
Noordzij, Walter
Knuuti, Juhani
deKemp, Robert A.
Slart, Riemer H. J. A.
Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview
title Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview
title_full Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview
title_fullStr Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview
title_full_unstemmed Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview
title_short Phase analysis of gated PET in the evaluation of mechanical ventricular synchrony: A narrative overview
title_sort phase analysis of gated pet in the evaluation of mechanical ventricular synchrony: a narrative overview
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908565/
https://www.ncbi.nlm.nih.gov/pubmed/30834496
http://dx.doi.org/10.1007/s12350-019-01670-7
work_keys_str_mv AT juarezorozcoluiseduardo phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview
AT monroygonzalezandrea phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview
AT prakkenniekhj phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview
AT noordzijwalter phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview
AT knuutijuhani phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview
AT dekemproberta phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview
AT slartriemerhja phaseanalysisofgatedpetintheevaluationofmechanicalventricularsynchronyanarrativeoverview