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Evolution of imprinting via lineage-specific insertion of retroviral promoters

Imprinted genes are expressed from a single parental allele, with the other allele often silenced by DNA methylation (DNAme) established in the germline. While species-specific imprinted orthologues have been documented, the molecular mechanisms underlying the evolutionary switch from biallelic to i...

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Detalles Bibliográficos
Autores principales: Bogutz, Aaron B., Brind’Amour, Julie, Kobayashi, Hisato, Jensen, Kristoffer N., Nakabayashi, Kazuhiko, Imai, Hiroo, Lorincz, Matthew C., Lefebvre, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908575/
https://www.ncbi.nlm.nih.gov/pubmed/31831741
http://dx.doi.org/10.1038/s41467-019-13662-9