Cargando…
Glycogen Synthase Kinase-3β Inhibition with 9-ING-41 Attenuates the Progression of Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with a median survival of 3 years after diagnosis. Although the etiology of IPF is unknown, it is characterized by extensive alveolar epithelial cell apoptosis and proliferation of myofibroblasts in the lungs. While the o...
Autores principales: | Jeffers, Ann, Qin, Wenyi, Owens, Shuzi, Koenig, Kathleen B., Komatsu, Satoshi, Giles, Francis J., Schmitt, Daniel M., Idell, Steven, Tucker, Torry A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908609/ https://www.ncbi.nlm.nih.gov/pubmed/31831767 http://dx.doi.org/10.1038/s41598-019-55176-w |
Ejemplares similares
-
TGF-β regulation of the uPA/uPAR axis modulates mesothelial-mesenchymal transition (MesoMT)
por: Logan, Ranisha, et al.
Publicado: (2021) -
Organizing empyema induced in mice by Streptococcus pneumoniae: effects of plasminogen activator inhibitor-1 deficiency
por: Tucker, Torry A., et al.
Publicado: (2016) -
KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis
por: Kamata, Hirotoshi, et al.
Publicado: (2017) -
Update on Novel Targeted Therapy for Pleural Organization and Fibrosis
por: Tucker, Torry A., et al.
Publicado: (2022) -
Clinical activity of 9-ING-41, a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, in refractory adult T-Cell leukemia/lymphoma
por: Hsu, Andrew, et al.
Publicado: (2022)