Cargando…
Exploring inflammatory signatures in arthritic joint biopsies with Spatial Transcriptomics
Lately it has become possible to analyze transcriptomic profiles in tissue sections with retained cellular context. We aimed to explore synovial biopsies from rheumatoid arthritis (RA) and spondyloarthritis (SpA) patients, using Spatial Transcriptomics (ST) as a proof of principle approach for unbia...
Autores principales: | Carlberg, Konstantin, Korotkova, Marina, Larsson, Ludvig, Catrina, Anca I., Ståhl, Patrik L., Malmström, Vivianne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908624/ https://www.ncbi.nlm.nih.gov/pubmed/31831833 http://dx.doi.org/10.1038/s41598-019-55441-y |
Ejemplares similares
-
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium
por: Vickovic, Sanja, et al.
Publicado: (2022) -
Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis
por: Hardt, Uta, et al.
Publicado: (2022) -
Semla: a versatile toolkit for spatially resolved transcriptomics analysis and visualization
por: Larsson, Ludvig, et al.
Publicado: (2023) -
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation
por: Mijnheer, Gerdien, et al.
Publicado: (2021) -
Identification and transfer of spatial transcriptomics signatures for cancer diagnosis
por: Yoosuf, Niyaz, et al.
Publicado: (2020)