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Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)
Factor VII (FVII) activating protease (FSAP) is a circulating serine protease. Human genetic studies, based on the Marburg I (MI) (Gly221Glu, chymotrypsin numbering system) polymorphism, implicate FSAP in the pathogenesis of many diseases. Here, we describe the molecular and functional changes cause...
Autores principales: | Nielsen, Nis V., Roedel, Elfie, Manna, Dipankar, Etscheid, Michael, Morth, Jens Preben, Kanse, Sandip M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908674/ https://www.ncbi.nlm.nih.gov/pubmed/31831842 http://dx.doi.org/10.1038/s41598-019-55531-x |
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