Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling

The development of perspective diagnostic techniques in medicine requires efficient high-throughput biological sample analysis methods. Here, we present an inline cartridge extraction that facilitates the screening rate of mass spectrometry shotgun lipidomic analysis of tissue samples. We illustrate...

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Autores principales: Pekov, Stanislav I., Eliferov, Vasily A., Sorokin, Anatoly A., Shurkhay, Vsevolod A., Zhvansky, Evgeny S., Vorobyev, Alexander S., Potapov, Alexander A., Nikolaev, Eugene N., Popov, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908710/
https://www.ncbi.nlm.nih.gov/pubmed/31831871
http://dx.doi.org/10.1038/s41598-019-55597-7
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author Pekov, Stanislav I.
Eliferov, Vasily A.
Sorokin, Anatoly A.
Shurkhay, Vsevolod A.
Zhvansky, Evgeny S.
Vorobyev, Alexander S.
Potapov, Alexander A.
Nikolaev, Eugene N.
Popov, Igor A.
author_facet Pekov, Stanislav I.
Eliferov, Vasily A.
Sorokin, Anatoly A.
Shurkhay, Vsevolod A.
Zhvansky, Evgeny S.
Vorobyev, Alexander S.
Potapov, Alexander A.
Nikolaev, Eugene N.
Popov, Igor A.
author_sort Pekov, Stanislav I.
collection PubMed
description The development of perspective diagnostic techniques in medicine requires efficient high-throughput biological sample analysis methods. Here, we present an inline cartridge extraction that facilitates the screening rate of mass spectrometry shotgun lipidomic analysis of tissue samples. We illustrate the method by its application to tumor tissue identification in neurosurgery. In perspective, this high-performance method provides new possibilities for the investigation of cancer pathogenesis and metabolic disorders.
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spelling pubmed-69087102019-12-16 Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling Pekov, Stanislav I. Eliferov, Vasily A. Sorokin, Anatoly A. Shurkhay, Vsevolod A. Zhvansky, Evgeny S. Vorobyev, Alexander S. Potapov, Alexander A. Nikolaev, Eugene N. Popov, Igor A. Sci Rep Article The development of perspective diagnostic techniques in medicine requires efficient high-throughput biological sample analysis methods. Here, we present an inline cartridge extraction that facilitates the screening rate of mass spectrometry shotgun lipidomic analysis of tissue samples. We illustrate the method by its application to tumor tissue identification in neurosurgery. In perspective, this high-performance method provides new possibilities for the investigation of cancer pathogenesis and metabolic disorders. Nature Publishing Group UK 2019-12-12 /pmc/articles/PMC6908710/ /pubmed/31831871 http://dx.doi.org/10.1038/s41598-019-55597-7 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pekov, Stanislav I.
Eliferov, Vasily A.
Sorokin, Anatoly A.
Shurkhay, Vsevolod A.
Zhvansky, Evgeny S.
Vorobyev, Alexander S.
Potapov, Alexander A.
Nikolaev, Eugene N.
Popov, Igor A.
Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
title Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
title_full Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
title_fullStr Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
title_full_unstemmed Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
title_short Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
title_sort inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908710/
https://www.ncbi.nlm.nih.gov/pubmed/31831871
http://dx.doi.org/10.1038/s41598-019-55597-7
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