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Generation of ECG signals from a reaction-diffusion model spatially discretized

We propose a model to generate electrocardiogram signals based on a discretized reaction-diffusion system to produce a set of three nonlinear oscillators that simulate the main pacemakers in the heart. The model reproduces electrocardiograms from healthy hearts and from patients suffering various we...

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Detalles Bibliográficos
Autores principales: Quiroz-Juárez, M. A., Jiménez-Ramírez, O., Vázquez-Medina, R., Breña-Medina, V., Aragón, J. L., Barrio, R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908715/
https://www.ncbi.nlm.nih.gov/pubmed/31831864
http://dx.doi.org/10.1038/s41598-019-55448-5
Descripción
Sumario:We propose a model to generate electrocardiogram signals based on a discretized reaction-diffusion system to produce a set of three nonlinear oscillators that simulate the main pacemakers in the heart. The model reproduces electrocardiograms from healthy hearts and from patients suffering various well-known rhythm disorders. In particular, it is shown that under ventricular fibrillation, the electrocardiogram signal is chaotic and the transition from sinus rhythm to chaos is consistent with the Ruelle-Takens-Newhouse route to chaos, as experimental studies indicate. The proposed model constitutes a useful tool for research, medical education, and clinical testing purposes. An electronic device based on the model was built for these purposes